Abstract: Two new labdanoids, forskolin E and F, with forskolin A, B, C and D, have been isolated from the chloroform extract of the whole plants of Coleus forskohlii. The chemical structures of the two minor constituents have been established as lα, 7β- diacetoxy- 8,13 epoxy- 6β- hydroxylabd- 14- en- 11 - one(l) and 7β-acetoxy- 8,13 - epoxy- 6β,9a- dihydroxylabd - 14- en- 11 - one(2), respectively, on the basis of detailed spectroscopic analysis and all assignments were supported by 1H -1H COSY, HMBC and HMOC spectrum (see table 1).

Key words: Forskolin E and F

摘要： 从唇形科毛喉鞘蕊花（Coleus forskohlii）全草的的氯仿提取物分离到2个新的微量成分，鞘蕊花戊素和已素。基于光谱分析，鞘蕊花戊素和已素的化学结构分别鉴定为lα，7β-二乙酸氧基-8，13-环氧-6β羟基勒丹-14烯-11-酮（1）和7β-乙酰氧基-8, 13环氧-6β，9α-二羟基勒丹-14烯-11-酮（2）。

关键词: 鞘蕊花戊素, 鞘蕊花已素, 毛喉鞘蕊花, 唇形科, 二维核磁共振谱