Abstract: Six compounds: morusin (1), mulberrofuran D (2), kuwanon H (3), mulberrofuran K(4), kuwanon G (5), mulberrofuran G (6) were isolated from root bark of Morus alba and their derivatives were prepared. Anti-HIV activity of these fourteen compounds were tested. Morusin, morusin 4''-glucoside and kuwanon H show positive activity.

Key words: Morus alba

摘要： 从中药桑白皮(Morus alba L.)的根皮中分离到6个成分，它们是：morusin(l)，mulberrofuran D(2)，kuwanon H(3)，mulberrofuran K(4)，kuwanon G(5)，mulberrofuran G(6)；并制备了它们的乙酰化合物和葡萄糖甙;还测定了这些化合物的体外抗人爱滋病病毒(HIV)活性和对人淋巴细胞的细胞毒活性，发现其中黄酮 morusin,kuwanon H和morusin 4'-glucoside具有一定的抗HIV活性。

关键词: 桑白皮, 黄酮, 抗人爱滋病病毒